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## Tesamorelin & Ipamorelin Blend: Synergistic Potential in Pituitary Cells



Tesamorelin is a synthetic analogue of growth hormone-releasing hormone (GHRH) that stimulates the anterior pituitary to release endogenous growth hormone (GH). Ipamorelin, on the other hand, is a selective ghrelin receptor agonist that also promotes GH secretion but with greater stability and fewer side effects. When combined, these peptides can produce a synergistic effect in pituitary cells: tesamorelin activates GHRH receptors while ipamorelin binds to growth hormone secretagogue receptors (GHS-R1a), leading to amplified GH release. ipamorelin side effects cancer enhances the magnitude of the response but also prolongs the duration, potentially improving clinical outcomes for conditions such as HIV-